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CISA Known Exploited Vulnerability
This CVE is actively exploited in the wild. CISA mandates federal agencies to patch immediately.
CVE

CVE-2025-20281

10.0
CVSScritical
Exploitable remotely over the internet · no authentication required.
Description

A vulnerability in a specific API of Cisco ISE and Cisco ISE-PIC could allow an unauthenticated, remote attacker to execute arbitrary code on the underlying operating system as root. The attacker does not require any valid credentials to exploit this vulnerability. This vulnerability is due to insufficient validation of user-supplied input. An attacker could exploit this vulnerability by submitting a crafted API request. A successful exploit could allow the attacker to obtain root privileges on an affected device.

Attack Vector
Network
Privileges Req.
None
User Interaction
None
cisco identity services engine software
Updated Nov 10, 2026View on NVD →
S4E scanner

Cisco ISE - Remote Code Execution

A vulnerability in a specific API of Cisco ISE and Cisco ISE-PIC could allow an unauthenticated, remote attacker to execute arbitrary code on the underlying operating system as root. The attacker does not require any valid credentials to exploit this vulnerability. This vulnerability is due to insufficient validation of user-supplied input. An attacker could exploit this vulnerability by submitting a crafted API request. A successful exploit could allow the attacker to obtain root privileges on an affected device. References: https://sec.cloudapps.cisco.com/security/center/content/CiscoSecurityAdvisory/cisco-sa-ise-unauth-rce-ZAd2GnJ6 https://www.zerodayinitiative.com/blog/2025/7/24/cve-2025-20281-cisco-ise-api-unauthenticated-remote-code-execution-vulnerability https://nvd.nist.gov/vuln/detail/CVE-2025-20281 Remediation: Update to the latest available version.

Used 20 times · 10 assets checked · domain, subdomain, ipv4

CVE history: cisco identity services engine software

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